The Choice: 1. Bison: calories: 190 kcal; fat: 5 g; cholesterol: 65 mg. 2. Beef: Calories: 466 kcal; Fat: 37 g; Cholesterol: 119 mg. 1, 2, Bison Tenderloin (High Plains, LLC) independent lab study, separate lean and fat, trimmed to 1/8 inch fat, raw. In comparison to USDA data for beef tenderloin. High Plains Bison Tenderloin has 190 calories, 5 g of fat and 65 mg of cholesterol compared to 466 calories, 37 g of fat and 119 mg of cholesterol in beef tenderloin. 59% fewer calories. 86% less fat. 45% less cholesterol compared to USDA data for Beef Tenderloin. The smart choice. All natural (minimally processed, no artificial ingredients). Always. No hormones (The USDA does not permit the use of hormones in raising bison). No antibiotics. Delicious for grilling. Chilled Exclusively by Air: Our 100% pure bison is Chilled Exclusively by Air and humanely processed under strict guidelines to provide the best tasting, highest quality meats. US inspected and passed by Department of Agriculture. HighPlainsBison.com. Visit HighPlainsBison.com to explore our collection of bison cooking tips and recipes.